There are non-anthropomorphic (normal non human-like) animals in the Happy Tree Friends world. Like the Happy Tree Friends, they can be killed in bloody, gruesome ways. In other cases, they are the cause of a character's death.
- Main article: The Baboon
The Baboon appears in From A to Zoo. It is tormented by Cuddles and Toothy, and, as a result (though it may also have been from Sniffles's camera's flashing), goes rampant and kills Sniffles by tearing him apart, and eventually (possibly) causes the deaths of everyone still alive on the bus.
- Main article: The Cow
The Grizzly Bear
- Main article: The Grizzly Bear
The dolphins appear in Sea What I Found.
A monkey can be seen swinging on vines at the beginning of Idol Curiosity. In the same episode, numerous dead monkeys fall from the sky when Sniffles picks up The Cursed Idol. A monkey can be seen locked in a cage in Junk in the Trunk, it appears to be smoking a cigar.
- Main article: The Orca
The Orca appears in Snow Place to Go, in which it kills off many of the Happy Tree Friends still alive in the frozen wastelands.
Multi-colored rabbits can be seen on a shelf at the pet store in Doggone It.
- Main article: The Reindeer
A reindeer is featured in Reindeer Kringle, kicking Petunia multiple times in the face. The reindeer can also be seen from a distance in Milkin' It and Class Act. The reindeer makes another appearance in Just Be Claus as it is seen pulling Santa Lumpy's sleigh.
The Rhino makes an appearance in From A to Zoo, in which it is agitated by Cuddles burning its rump, and stabs Toothy through the face with its horn.
The Seal appears in Better Off Bread, in which it is suffering from an oil spill along with two gulls. Its body is set on fire after Splendid uses his heat vision to repair the leaking oil tanker nearby.
The Sea Lions
Two sea lions appear in Water You Wading For, where they bounce Cuddles back and forth to each other like a beach ball.
- Main article: The Whale
The Whale has appeared in 4 episodes. It first appears in Get Whale Soon as the whale that eats Lumpy and Russell. It then makes another appearance in Water You Wading For, in which it appears out of a pond and crushes Cuddles. Its third appearance is in A Change of Heart, in which it is seen dead, with an also dead Handy lying on it. Two whales appear in Mirror Mirror, Splendid uses a humpback whale to fight while Splendont uses a sperm whale. Because of the size of the former it blows Splendont's whale to pieces.
- For more information, see Canary
A canary that is seen in I Get a Trick Out of You. Lumpy kept it in his hat for his magic performance, but it ended up dying before the show. He throws the bird in the air, expecting it to fly away, but it only falls to the stage, prompting Lumpy to nervously kick it out of the way.
- Main article: The Eagle
The Eagle and her chicks are seen in Take a Hike, in which Flaky tries to help one of her chicks back into its nest and accidentally kills it and destroys the nest, provoking the mother to kill Flaky and use her carcass as a new nest for other chicks of hers.
- Main article: The Seagulls
These birds eat the guts of dead or dying Happy Tree Friends when they are at the beach/on the ocean. The Seagulls are featured in the episodes Wipe Out!, Better Off Bread, Sea What I Found, and Water Way to Go. The only time they ever actually kill someone is in Wipe Out!, in which they eat the injured and possibly dying Flaky.
- Main article: The Vultures
The vultures behave very much like The Seagulls, meaning that they will swarm and shred any corpse or helpless victim.
- Main article: The Woodpecker
A woodpecker that is seen in Hide and Seek, in which its pecking makes Flippy flip, and it is then killed by his bowie knife. It makes another appearance in Eye Candy, causing Toothy to fall off a cliff by pecking his eye. It also makes a cameo at the beginning of Eyes Cold Lemonade.
Reptiles and Amphibians
- Main article: List of Snakes
An alligator first appears in Water You Wading For as one of the creatures that attack Cuddles. A pet alligator is later seen in Junk in the Trunk, being held hostage with many other animals by Lifty and Shifty. An alligator can also be seen in the jungle level of Run and Bun.
A Frog is killed by The Mole in Every Litter Bit Hurts by being impaled with a litter spike, before being collected in a plastic bag. Another frog appears in Junk in the Trunk as one of the pets stolen by Lifty and Shifty.
Pterosaur is a non-anthropomorphic animal that appears in Dino-Sore Days.
The Dinosaur is a non-anthropomorphic animal in Dino-Sore Days.
- Main article: The Sharks
The first sharks appear in Happy Trails Pt. 2: Jumping the Shark, swimming around the island. One of them kills Lifty and Shifty, and their fins are grayish-colored. Another shark makes an appearance in Petunia's Summer Smoochie, this one peach-colored. Sharks also appear in the TV series in the episodes Wipe Out! and Wingin' It. In these episodes, they are blue in color. They almost eat Flaky in these episodes, and, although she is injured by one in Wingin' It, she is never actually killed by one. They are voiced by Aubrey Ankrum and Kenn Navarro.
Various Marine Life
These marine animals (consisting of a sawfish, a hammerhead shark, and an electric eel) are seen in Sea What I Found, in which Russell uses them to build a sea vessel to chase after Lifty & Shifty. However, this does not work and the sea creatures viciously attack him.
The Bees make their first appearance in Sweet Ride, in which they kill Nutty when his head gets stuck in a beehive. They appear again in Take a Hike, this time showing no hostility to Nutty when he is slurping honey from a hive. In Aw, Shucks!, a beehive is knocked off its branch and some bees swarm around Toothy (though these might be wasps, as Toothy did not get an allergic reaction to their stings). One bee appears in The Carpal Tunnel of Love and stings Toothy in the eye, causing it to get infected. It comes back later and kills Lumpy when it stings his eye, causing him to crash into the back of a truck.
The Giant Squid
- Main article: The Giant Squid
The Giant Squid first appears in Doggone It. It was a pet until it attacked and killed several characters before being captured by Lumpy. It appears again in You're Kraken Me Up, causing more carnage after Russell accidentally awakens it by dropping an anchor on its head.
The Hermit Crab
This small blue crab appears in Wipe Out!. It is first seen replacing its old shell with an ice cream cone, nearly being stepped on by Lumpy in the process. At the end of the episode, it uses Flaky's severed head as its new shell.
The ButterflyThe Butterfly appears in Idol Curiosity
snail.png|The snail before its death in Every Litter Bit Hurts. Seeing eye tortose.png|Seeing eye snail?
Flesh-Eating FlowersFlesh-Eating Flowers appear in Idol Curiosity.