This article focuses on the interactions of Giggles and every other main character of Happy Tree Friends.
Giggles is arguably one of the most popular characters, as she is friends with most of the Happy Tree Friends and has interacted with every single character. This can be concluded to be since Giggles is happy, cheerful, and friendly towards everyone with very few exceptions. It can also be concluded that several male characters have crushes on her, as she has dated quite a few of them and a lot of them are shown to have feelings for her (most primarily Cuddles and Disco Bear).
- Main article: Cuddles-Giggles Relationship
Initially, Cuddles and Giggles were depicted as friends, but as the series progressed, they started becoming depicted as a couple.
Toothy and Giggles are friends most of the time when they appears together.
In Class Act, Giggles like everyone else, was awed by Toothy's singing. In Blast from the Past, she comforts him after he injures himself. After Sniffles turns back time for the first time, they are seen holding hands and playing with Lumpy and Cuddles. She also sat next to Toothy, and Nutty, at the theaters in Happy New Year. Toothy was also one of the five characters that she mourned in Happy Trails Pt. 2: Jumping the Shark. Despite how they are often seen with Cuddles and Lumpy, they rarely interact with each other alone.
- Main article: Giggles-Lumpy Relationship
Lumpy and Giggles are friends most of the time, but due to the fact that they are usually put on different sides of the story, their personalities have clashed and their friendship usually falls apart. A key example of this is in Every Litter Bit Hurts.
- Main article: Petunia-Giggles Relationship
Petunia is Giggles' best friend on the show, but this is likely because of Flaky's shyness and Lammy's late debut, so they did not have any other friends of their gender to play with. They are one of the very few friendships who have never fought or became rivals.
Handy is usually seen getting along well with Giggles, but unlike Handy's relationship with Petunia, Giggles and Handy are portrayed as nothing more than good friends. However, despite that, Giggles is one of the few characters Handy appears to regularly respect or even fond of.
In Happy Trails Pt. 2: Jumping the Shark, Giggles cries on Handy when they're are mourning the deaths of over characters. In Home Is Where the Hurt Is, Giggles hugs him after he builds her a house, but the happiness does not last long as the house soon falls apart. Giggles also serves Handy's breakfast in Concrete Solution.
Like Cuddles, Giggles isn't very fond of Nutty. They rarely appear together, and when they do, it is either in a group as in Remains to be Seen, I Get a Trick Out of You, Mime to Five, or there is always some sort of trouble. In Class Act, Giggles is horrified at the sight of Nutty biting Sniffles under the belief that Sniffles was a candy cane.
In Dunce Upon a Time, Giggles and Nutty are shown to be living together in poverty. Giggles becomes annoyed with Nutty after he swaps their emaciated cow for jelly beans when he was supposed to sell the cow at the market instead. In this episode, their relationship is exactly unclear. It's unknown if their a couple or siblings.
In Concrete Solution, after serving Nutty his pancakes she gives off an expression when she gives him syrup that appears to show that Giggles is aware about how much Nutty loves sugar. In Happy New Year, Giggles sits next to him, and Toothy, at the theaters. In The Wrong Side of the Tracks, he goes to the carnival with him.
Giggles sees Sniffles as a great friend. They go exploring together in Idol Curiosity, they both work together to rid the lake of trash in Every Litter Bit Hurts, and they both go on a haunted ride together in Boo Do You Think You Are?, she also cries over his death and will later do this again in See You Later, Elevator. She also tried to save Sniffles from Giant Lumpy in Dunce Upon a Time
Giggles' only major interaction with Pop is in Every Litter Bit Hurts, in which Pop is hired by Giggles to clean Lumpy's environmental crimes, also bringing Cub along. She was also admired by Pop and Cub's Christmas lights in Stealing the Spotlight.
In Wingin' It, Giggles gets annoyed at Cub hitting her seat with his toy airplane and Pop doing nothing to stop him.
Giggles' only direct interaction with Cub is in Wingin' It, in which Cub plays with his toy airplane and wakes her up, much to her annoyance. She also briefly interacted with Cub in Cubtron Z as she and Petunia are picked up and smashed against a building. Both characters were also suppose to eat a Christmas dinner together in Kringle Feast. She was also admired by the Christmas lights Pop and Cub made in Stealing the Spotlight.
Flaky and Giggles are often seen getting along well and appear to be close friends. While Giggles and Petunia are better friends to each other, Giggles interacts with Flaky more then Petunia.
Early on, Flaky, Sniffles, and Giggles are together in a haunted house in Boo Do You Think You Are?. Later on, they are seen in an exploration team lead by Sniffles in Idol Curiosity. They both also went trick-or-treating, along with Lumpy in Out of Sight, Out of Mime and in This Is Your Knife they went camping with Cuddles. In Dunce Upon a Time, Giggles tries to save her from Giant Lumpy.
Later on, in Royal Flush, when Flaky is embarrassed about coming in, Giggles, along with Petunia and Lammy, feel awkward about it first. However, she quickly lets it go and encourages Flaky to come in and play poker with them.
The Mole is a friend of Giggles, and he appears to have a reoccurring crush on her. In Blind Date, Giggles was suppose to go on a date with him. In Cold Hearted, after Toothy interrupts Giggles' date with Cro-Marmot, she is then seen going out on a date with The Mole.
In none romantic instances, Giggles cried over The Mole's death in Happy Trails Pt. 2: Jumping the Shark. Giggles and The Mole sit together at a circus Mime to Five. Giggles also narrowly avoids being run over by The Mole in Spare Tire. In Every Litter Bit Hurts, Giggles hires The Mole (despite his lack of vision) to help clean the lake. At the end of the episode, however, Giggles realizes her mistake when The Mole uses the trash pick she gave him to pierce her heart out, mistaking it for a piece of litter.
- Main article: Disco Bear-Female characters Relationship
In Disco Bear's debut in Stayin' Alive, Giggles is somewhat nicer towards him (as opposed to in later episodes) when he attempts to hit on Petunia and her. She is even seen smiling when Disco Bear pulls her close to dance with her. However, he accidentally spins her into a teapot and Petunia into an electric fence, causing both to hold a grudge against him.
Despite being considered one of the nicer characters she has made fun of Disco Bear on several occasions. Most of the time when they interact Giggles just moans or rolls her eyes, in Ipso Fatso and Easy Comb, Easy Go she openly laughs at him when Petunia calls him a square and when he flirts with his bald head.
In a strangely out of character moment, Giggles actually favorited a YouTube video made by Disco Bear in YouTube 101: Subscriptions, the video involving Disco Bear drinking with a cardboard version of herself.
- Main article: Russell-Giggles Relationship
One of Russell's major interactions with Giggles is in Sea of Love, in which they are on a date on a rowboat in the ocean.
Their second date is in You're Kraken Me Up, only this time they are interrupted by a giant squid. They finally have a perfect meeting in Put Your Back Into It, in which Giggles comes to Russell's house for dinner. Both characters also held hands together in Class Act.
Like everyone else, Lifty and Shifty are usually seen stealing from Giggles. In Junk in the Trunk, they steal her cat along with everyone else's pets. In Gems the Breaks, they tie her and Petunia up and steal their profits from selling lemonade. On a positive note, they were suppose to eat a Christmas dinner together in Kringle Feast. They all also went trick-or-treating in Remains to be Seen.
Despite Giggles being attracted to Mime's new wig in Easy Comb, Easy Go, Giggles has not on any other occasion shown any feelings towards Mime other than friendship. Her flirting with Mime was likely to get back at Disco Bear, mocking his baldness.
Giggles has cried over Mime's deaths in two instances, See You Later, Elevator and Happy Trails Pt. 2: Jumping the Shark. Giggles also attempted to rescue Mime from Giant Lumpy in Dunce Upon a Time. They are seen getting breakfast with Petunia in Who's to Flame?.
- Main article: Giggles-Cro-Marmot Relationship
Giggles is good friends with Cro-Marmot. In Snow What? That's What!, Giggles, worried for his safety, chases after Cro-Marmot after accidentally throwing a snowball at him and causing him to slide off a cliff.
In Cold Hearted, she goes on a date with him, but after Toothy interrupts it, she dumps him to be with The Mole. Giggles and Petunia kiss him after he wins in Wipe Out!. Unfortunately, since he is frozen in a block of ice, their lips get stuck to the ice and they are forced to tear them off to get away.
- Main article: Flippy-Giggles relationship
Flippy and Giggles are shown to be close friends who interact in several episodes. However, Giggles is his evil self's most frequent victim. In On My Mind, Flippy is shown to have a crush on Giggles.
- Main article: Splendid-Giggles Relationship
Like most characters, Giggles is a fan of Splendid despite his inability to do his job properly. In most of their appearances together, Giggles is the damsel in distress with Splendid having to save her (and accidentally kill her seconds after).
So far, Lammy and Giggles have only interacted in Royal Flush, in which they play poker along with Flaky and Petunia, she does start to get bored after a while.
Mr. Pickels tries to kill her in Royal Flush. Before this happens Giggles actually acknowledges Mr. Pickels when she notices his body on the table.
- Giggles and Lumpy are the only characters to have interacted with every single main character in the series.
- The only male characters Giggles hasn't dated, flirted with or shown affection towards but has interacted with are Toothy, Handy, Nutty, Sniffles, Pop. Cub, Disco Bear, and Lifty & Shifty.